Clinical characteristics and frequency of TLR4 polymorphisms in Brazilian patients with ankylosing spondylitis

ABSTRACT Objectives: Innate immunity is involved in the physiopathology of ankylosing spondylitis (AS), with the participation of Gram-negative bacteria, modulation of human leukocyte antigen (HLA) B27 and the involvement of pattern recognition receptors, such as Toll-like receptors (TLRs). The aim...

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Main Authors: Natalia Pereira Machado, Eliana Nogueira, Karen Oseki, Pâmela Carolina Cruz Ebbing, Clarice Silvia Taemi Origassa, Tatiane Mohovic, Niels Olsen Saraiva Câmara, Marcelo de Medeiros Pinheiro
Format: Article
Language:English
Published: Sociedade Brasileira de Reumatologia
Series:Revista Brasileira de Reumatologia
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042016000500432&lng=en&tlng=en