Insights on Foxn1 Biological Significance and Usages of the “Nude” Mouse in Studies of T-Lymphopoiesis
<p>Mutation in the “nude” gene, i.e. the <i>FoxN1</i> gene, induces a hairless phenotype and a rudimentary thymus gland in mice (nude mouse) and humans (T-cell related primary immunodeficiency). Conventional <i>FoxN1</i> gene knockout and transgenic...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2012-01-01
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| Series: | International Journal of Biological Sciences |
| Online Access: | http://www.biolsci.org/v08p1156.htm |