Cytoplasmic Overexpression of CD95L in Esophageal Adenocarcinoma Cells Overcomes Resistance to CD95-Mediated Apoptosis

Introduction: The CD95/CD95L pathway plays a critical role in tissue homeostasis and immune system regulation; however, the function of this pathway in malignancy remains poorly understood. We hypothesized that CD95L expression in esophageal adenocarcinoma confers advantages to the neoplasm other t...

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Bibliographic Details
Main Authors: Gregory A. Watson, Sanjay Naran, Xinglu Zhang, Michael T. Stang, Pierre E. Queiroz de Oliveira, Steven J. Hughes
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800680