Experimental Stroke Differentially Affects Discrete Subpopulations of Splenic Macrophages

Changes to the immune system after stroke are complex and can result in both pro-inflammatory and immunosuppressive consequences. Following ischemic stroke, brain resident microglia are activated and circulating monocytes are recruited to the injury site. In contrast, there is a systemic deactivatio...

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Bibliographic Details
Main Authors: Laura McCulloch, Alessio Alfieri, Barry W. McColl
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01108/full