Immunotoxin-Induced Ablation of the Intrinsically Photosensitive Retinal Ganglion Cells in Rhesus Monkeys

Immunotoxin-Induced Ablation of the Intrinsically Photosensitive Retinal Ganglion Cells in Rhesus Monkeys

Purpose: Intrinsically photosensitive retinal ganglion cells (ipRGCs) contain the photopigment melanopsin, and are primarily involved in non-image forming functions, such as the pupillary light reflex and circadian rhythm entrainment. The goal of this study was to develop and validate a targeted ipR...

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Bibliographic Details
Main Authors: Lisa A. Ostrin, Christianne E. Strang, Kevin Chang, Ashutosh Jnawali, Li-Fang Hung, Baskar Arumugam, Laura J. Frishman, Earl L. Smith, Paul D. Gamlin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neurology
Subjects:
melanopsin
ipRGCs
intrinsically photosensitive retinal ganglion cells
immunotoxin
pupil
rhesus monkey
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.01000/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.01000/full

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