Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics.

Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics.

Loss-of-function of the potassium-chloride cotransporter 3 (KCC3) causes hereditary motor and sensory neuropathy with agenesis of the corpus callosum (HMSN/ACC), a severe neurodegenerative disease associated with defective midline crossing of commissural axons in the brain. Conversely, KCC3 over-exp...

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Bibliographic Details
Main Authors: Adèle Salin-Cantegrel, Masoud Shekarabi, Sarah Rasheed, François M Charron, Janet Laganière, Rebecca Gaudet, Patrick A Dion, Jean-Yves Lapointe, Guy A Rouleau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3665532?pdf=render

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http://europepmc.org/articles/PMC3665532?pdf=render

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