Effects of human Toll-like receptor 1 polymorphisms on ageing

<p>Abstract</p> <p>Background</p> <p>Advanced age results in crucial alterations of the innate and adaptive immune system leading to functional defects resulting in infection and chronic diseases. Toll-like receptors (TLR) recognize pathogenic structures and are importa...

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Bibliographic Details
Main Authors: Uciechowski Peter, Oellig Eva Maria, Mariani Erminia, Malavolta Marco, Mocchegiani Eugenio, Rink Lothar
Format: Article
Language:English
Published: BMC 2013-02-01
Series:Immunity & Ageing
Subjects:
SNP
Online Access:http://www.immunityageing.com/content/10/1/4