Mitochondrial Protein PINK1 Positively Regulates RLR Signaling

The serine/threonine kinase phosphatase and tensin homolog (PTEN)-induced putative kinase 1(PINK1) controls mitochondrial quality and plays a vital role in the pathogenesis of early-onset Parkinson's disease. However, whether PINK1 has functions in innate antiviral immunity is largely unknown....

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Bibliographic Details
Main Authors: Jun Zhou, Rui Yang, Zhaoru Zhang, Qianru Liu, Yuanyuan Zhang, Qingqing Wang, Hongbin Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
RLR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01069/full