The Efficacy of Methotrexate-Impregnated Hydroxyapatite Composites on Human Mammary Carcinoma Cells
Purpose. To investigate the efficacy of local biodegradable composites of hydroxyapatite, plaster of Paris, and a binder of either alginate or chitosan impregnated with methotrexate on human mammary carcinoma cells. Methods. An in vitro analysis of drug dissolution and a cytotoxicity test on human m...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2007-04-01
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Series: | Journal of Orthopaedic Surgery |
Online Access: | https://doi.org/10.1177/230949900701500113 |