The Efficacy of Methotrexate-Impregnated Hydroxyapatite Composites on Human Mammary Carcinoma Cells

Purpose. To investigate the efficacy of local biodegradable composites of hydroxyapatite, plaster of Paris, and a binder of either alginate or chitosan impregnated with methotrexate on human mammary carcinoma cells. Methods. An in vitro analysis of drug dissolution and a cytotoxicity test on human m...

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Bibliographic Details
Main Authors: J Vechasilp, B Tangtrakulwanich, K Oungbho, S Yuenyongsawad
Format: Article
Language:English
Published: SAGE Publishing 2007-04-01
Series:Journal of Orthopaedic Surgery
Online Access:https://doi.org/10.1177/230949900701500113