Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway

Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway

Two ATP-binding cassette transporter proteins, ABCA1 and ABCG1, may mediate an active efflux of cellular cholesterol and phospholipids. They are ubiquitously expressed and are subject to regulation by cholesterol loading or by treatment with agents that activate the nuclear hormone receptor LXR. Ear...

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Bibliographic Details
Main Authors: Rebecca Kaplan, Xiaodong Gan, John G. Menke, Samuel D. Wright, Tian-Quan Cai
Format: Article
Language:English
Published: Elsevier 2002-06-01
Series:Journal of Lipid Research
Subjects:
LPS
HDL
lipid transporter
regulation
nuclear hormone receptor
CYP7A
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520304703

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http://www.sciencedirect.com/science/article/pii/S0022227520304703

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