The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose

The Contribution of Cytomegalovirus Infection to Immune Senescence Is Set by the Infectious Dose

The relationship between human cytomegalovirus (HCMV) infections and accelerated immune senescence is controversial. Whereas some studies reported a CMV-associated impaired capacity to control heterologous infections at old age, other studies could not confirm this. We hypothesized that these discre...

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Bibliographic Details
Main Authors: Anke Redeker, Ester B. M. Remmerswaal, Esmé T. I. van der Gracht, Suzanne P. M. Welten, Thomas Höllt, Frits Koning, Luka Cicin-Sain, Janko Nikolich-Žugich, Ineke J. M. ten Berge, René A. W. van Lier, Vincent van Unen, Ramon Arens
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
CMV
memory CD8 T cells
immunesenesence
mouse models
memory inflation
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01953/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01953/full

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