Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy
<p>Abstract</p> <p>The vacuolar ATPases are ATP-dependent proton pumps whose functions include the acidification of intracellular compartments and the extrusion of protons through the cell cytoplasmic membrane. These pumps play a pivotal role in the regulation of cell pH in normal...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-05-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Online Access: | http://www.jeccr.com/content/29/1/44 |