Proton pump inhibitors as anti vacuolar-ATPases drugs: a novel anticancer strategy

<p>Abstract</p> <p>The vacuolar ATPases are ATP-dependent proton pumps whose functions include the acidification of intracellular compartments and the extrusion of protons through the cell cytoplasmic membrane. These pumps play a pivotal role in the regulation of cell pH in normal...

Full description

Bibliographic Details
Main Authors: Fais Stefano, Citro Gennaro, Spugnini Enrico P
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/29/1/44