Single-Cell RNA-seq Reveals Characteristics of Malignant Cells and Immune Microenvironment in Subcutaneous Panniculitis-Like T-Cell Lymphoma

Single-Cell RNA-seq Reveals Characteristics of Malignant Cells and Immune Microenvironment in Subcutaneous Panniculitis-Like T-Cell Lymphoma

BackgroundSubcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a malignant primary T-cell lymphoma that is challenging to distinguish from autoimmune disorders and reactive panniculitides. Delay in diagnosis and a high misdiagnosis rate affect the prognosis and survival of patients. The difficu...

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Bibliographic Details
Main Authors: Zifeng Li, Hongsheng Wang, Rui Dong, Jie Man, Li Sun, Xiaowen Qian, Xiaohua Zhu, Ping Cao, Yi Yu, Jun Le, Yang Fu, Ping Wang, Wenjin Jiang, Chen Shen, Yangyang Ma, Lian Chen, Yaochen Xu, Jiantao Shi, Hui Zhang, Maoxiang Qian, Xiaowen Zhai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
single-cell RNA-seq (scRNA-seq)
T cell malignancies
pediatric oncology
molecular diagnoses
subcutaneous panniculitis- like T-cell lymphoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.611580/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.611580/full

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