Stem cell factor and granulocyte colony-stimulating factor promote brain repair and improve cognitive function through VEGF-A in a mouse model of CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is a cerebral small vascular disease caused by NOTCH3 gene mutation in vascular smooth muscle cells (VSMCs), leading to ischemic stroke and vascular dementia. To date, the pathogenesis of CADASIL rema...

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Bibliographic Details
Main Authors: Suning Ping, Xuecheng Qiu, Michele Kyle, Karen Hughes, John Longo, Li-Ru Zhao
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Neurobiology of Disease
Subjects:
SCF
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996119302293