Role of vitamin D3 in modulation of ΔNp63α expression during UVB induced tumor formation in SKH-1 mice.

Role of vitamin D3 in modulation of ΔNp63α expression during UVB induced tumor formation in SKH-1 mice.

ΔNp63α, a proto-oncogene, is up-regulated in non-melanoma skin cancers and directly regulates the expression of both Vitamin D receptor (VDR) and phosphatase and tensin homologue deleted on chromosome ten (PTEN). Since ΔNp63α has been shown to inhibit cell invasion via regulation of VDR, we wanted t...

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Bibliographic Details
Main Authors: Natasha T Hill, Gabriel H Gracia-Maldonado, Mary K Leonard, Amanda R Harper, Kathleen L Tober, Tatiana M Oberyszyn, Madhavi P Kadakia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4156396?pdf=render

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http://europepmc.org/articles/PMC4156396?pdf=render

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