Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly.

Keratins are cytoskeletal proteins that hierarchically arrange into filaments, starting with the dimer sub-unit. They are integral to the structural support of cells, in skin, hair and nails. In skin, keratin is thought to play a critical role in conferring the barrier properties and elasticity of s...

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Bibliographic Details
Main Authors: David J Bray, Tiffany R Walsh, Massimo G Noro, Rebecca Notman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4504709?pdf=render