Corticosterone induces rapid spinogenesis via synaptic glucocorticoid receptors and kinase networks in hippocampus.

BACKGROUND: Modulation of dendritic spines under acute stress is attracting much attention. Exposure to acute stress induces corticosterone (CORT) secretion from the adrenal cortex, resulting in rapid increase of CORT levels in plasma and the hippocampus. METHODOLOGY/PRINCIPAL FINDINGS: Here we demo...

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Bibliographic Details
Main Authors: Yoshimasa Komatsuzaki, Yusuke Hatanaka, Gen Murakami, Hideo Mukai, Yasushi Hojo, Minoru Saito, Tetsuya Kimoto, Suguru Kawato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3324490?pdf=render