Genetically-encoded tools for cAMP probing and modulation in living systems.

Genetically-encoded tools for cAMP probing and modulation in living systems.

Intracellular 3'-5'-cyclic adenosine monophosphate (cAMP) is one of the principal second messengers downstream of a manifold of signal transduction pathways, including the ones triggered by G protein-coupled receptors. Not surprisingly, biochemical assays for cAMP have been instrumental fo...

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Bibliographic Details
Main Authors: Valeriy M Paramonov, Veronika eMamaeva, Cecilia eSahlgren, Adolfo eRivero-Muller
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Pharmacology
Subjects:
cyclic nucleotide
optogenetics
biosensor
cAMP signaling
cell-based assays
genetically encoded probe
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00196/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00196/full

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