MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers

MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers

Abstract The Fanconi Anemia (FA) pathway is essential for human cells to maintain genomic integrity following DNA damage. This pathway is involved in repairing damaged DNA through homologous recombination. Cancers with a defective FA pathway are expected to be more sensitive to cross-link based ther...

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Bibliographic Details
Main Authors: Wenrui Duan, Shirley Tang, Li Gao, Kathleen Dotts, Andrew Fink, Arjun Kalvala, Brittany Aguila, Qi-En Wang, Miguel A. Villalona-Calero
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83884-9

Internet

https://doi.org/10.1038/s41598-021-83884-9

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