Interplay between Cytokine Circuitry and Transcriptional Regulation Shaping Helper T Cell Pathogenicity and Plasticity in Inflammatory Bowel Disease

Interplay between Cytokine Circuitry and Transcriptional Regulation Shaping Helper T Cell Pathogenicity and Plasticity in Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) is a chronic disorder manifested as Crohn’s disease (CD) and ulcerative colitis (UC) characterized by intestinal inflammation and involves a dysregulated immune response against commensal microbiota through the activation of CD4 T helper cells. T helper cell differen...

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Bibliographic Details
Main Authors: Shin-Huei Fu, Ming-Wei Chien, Chao-Yuan Hsu, Yu-Wen Liu, Huey-Kang Sytwu
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
T helper cells
cytokines
transcription factors
plasticity
transdifferentiation
conversion
Online Access:https://www.mdpi.com/1422-0067/21/9/3379

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https://www.mdpi.com/1422-0067/21/9/3379

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