Directed evolution of the PcaV allosteric transcription factor to generate a biosensor for aromatic aldehydes

Abstract Background Transcription factor-based biosensors are useful tools for the detection of metabolites and industrially valuable molecules, and present many potential applications in biotechnology and biomedicine. However, the most common approach to develop biosensors relies on employing a lim...

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Bibliographic Details
Main Authors: Leopoldo F. M. Machado, Andrew Currin, Neil Dixon
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Biological Engineering
Online Access:http://link.springer.com/article/10.1186/s13036-019-0214-z