Development of doxorubicin-loaded chitosan–heparin nanoparticles with selective anticancer efficacy against gastric cancer cells in vitro through regulation of intrinsic apoptosis pathway

Chitosan–heparin nanoparticles (CS-HP NPs) can be used as potential nano-based platforms for development of drug delivery carriers. In this article, doxorubicin (Dox)@CS-HP NPs were synthesized and their physicochemical characteristics were assessed. Afterwards, their anticancer effects against gast...

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Bibliographic Details
Main Authors: Huiyu Yang, Aimin Sun, Junxia Yang, Haowei Cheng, Xiaoang Yang, Hongtao Chen, Ding Huanfei, Mojtaba Falahati
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221002811