Ethanol Induces Extracellular Vesicle Secretion by Altering Lipid Metabolism through the Mitochondria-Associated ER Membranes and Sphingomyelinases

Ethanol Induces Extracellular Vesicle Secretion by Altering Lipid Metabolism through the Mitochondria-Associated ER Membranes and Sphingomyelinases

Recent evidence pinpoints extracellular vesicles (EVs) as key players in intercellular communication. Given the importance of cholesterol and sphingomyelin in EV biology, and the relevance of mitochondria-associated endoplasmic reticulum membranes (MAMs) in cholesterol/sphingomyelin homeostasis, we...

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Bibliographic Details
Main Authors: Francesc Ibáñez, Jorge Montesinos, Estela Area-Gomez, Consuelo Guerri, María Pascual
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
lipid metabolism
mitochondria-associated ER membranes
alcohol
neuroinflammation
microglia
Online Access:https://www.mdpi.com/1422-0067/22/16/8438

Internet

https://www.mdpi.com/1422-0067/22/16/8438

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