Network-based identification of critical regulators as putative drivers of human cleft lip

Network-based identification of critical regulators as putative drivers of human cleft lip

Abstract Background Cleft lip (CL) is one of the most common congenital birth defects with complex etiology. While genome-wide association studies (GWAS) have made significant advances in our understanding of mutations and their related genes with potential involvement in the etiology of CL, it rema...

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Bibliographic Details
Main Authors: Aimin Li, Guimin Qin, Akiko Suzuki, Mona Gajera, Junichi Iwata, Peilin Jia, Zhongming Zhao
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medical Genomics
Subjects:
Cleft lip
Feed forward loop
Regulatory network
Disease-causing gene
microRNA
Transcription factor
Online Access:http://link.springer.com/article/10.1186/s12920-018-0458-3

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http://link.springer.com/article/10.1186/s12920-018-0458-3

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