A single mutation in the 15S rRNA gene confers nonsense suppressor activity and interacts with mRF1 the release factor in yeast mitochondria

We have determined the nucleotide sequence of the mim3-1 mitochondrial ribosomal suppressor, acting on ochre mitochondrial mutations and one frameshift mutation in Saccharomyces cerevisiae. The 15s rRNA suppressor gene contains a G633 to C transversion. Yeast mitochondrial G633 corr...

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Bibliographic Details
Main Authors: Ali Gargouri, Catherine Macadré, Jaga Lazowska
Format: Article
Language:English
Published: Shared Science Publishers OG 2015-08-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/a-single-mutation-in-the-15s-rrna-gene-confers-non-sense-suppressor-activity-and-interacts-with-mrf1-the-release-factor-in-yeast-mitochondria/