Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

Abstract In this multi-institutional study we compiled a retrospective cohort of 86 posterior fossa tumors having received the diagnosis of cerebellar glioblastoma (cGBM). All tumors were reviewed histologically and subjected to array-based methylation analysis followed by algorithm-based classifica...

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Main Authors: Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Christian Koelsche, Annika K. Wefers, Azadeh Ebrahimi, Philipp Sievers, Kristin Huang, M. Belén Casalini, Francisco Fernández-Klett, Abigail Suwala, Michael Weller, Dorothee Gramatzki, Joerg Felsberg, Guido Reifenberger, Albert Becker, Volkmar H. Hans, Marco Prinz, Ori Staszewski, Till Acker, Hildegard Dohmen, Christian Hartmann, Werner Paulus, Katharina Heß, Benjamin Brokinkel, Jens Schittenhelm, Rolf Buslei, Martina Deckert, Christian Mawrin, Ekkehard Hewer, Ute Pohl, Zane Jaunmuktane, Sebastian Brandner, Andreas Unterberg, Daniel Hänggi, Michael Platten, Stefan M. Pfister, Wolfgang Wick, Christel Herold-Mende, Andrey Korshunov, David E. Reuss, Felix Sahm, David T. W. Jones, David Capper, Andreas von Deimling
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Acta Neuropathologica Communications
Subjects:
Cerebellar glioblastoma
Methylation-based classification
Copy number variation load
Anaplastic pilocytic astrocytoma
Anaplastic astrocytoma with piloid features
Integrated diagnosis
Online Access:http://link.springer.com/article/10.1186/s40478-019-0801-8

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http://link.springer.com/article/10.1186/s40478-019-0801-8

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