Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt
Both cell-cell and cell-matrix adhesion are important for epithelial cell differentiation and function. Classical cadherins mediate cell to cell interactions and are potent activators of the signal transducer and activator of transcription (Stat3), thereby offering survival signaling. While the epit...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2015-12-01
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Series: | Biomolecular Concepts |
Subjects: | |
Online Access: | https://doi.org/10.1515/bmc-2015-0022 |