Cell-cell and cell-matrix adhesion in survival and metastasis: Stat3 versus Akt

Both cell-cell and cell-matrix adhesion are important for epithelial cell differentiation and function. Classical cadherins mediate cell to cell interactions and are potent activators of the signal transducer and activator of transcription (Stat3), thereby offering survival signaling. While the epit...

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Bibliographic Details
Main Authors: Niit Maximilian, Hoskin Victoria, Carefoot Esther, Geletu Mulu, Arulanandam Rozanne, Elliott Bruce, Raptis Leda
Format: Article
Language:English
Published: De Gruyter 2015-12-01
Series:Biomolecular Concepts
Subjects:
akt
emt
fak
rac
Online Access:https://doi.org/10.1515/bmc-2015-0022