HapX positively and negatively regulates the transcriptional response to iron deprivation in Cryptococcus neoformans.

The fungal pathogen Cryptococcus neoformans is a major cause of illness in immunocompromised individuals such as AIDS patients. The ability of the fungus to acquire nutrients during proliferation in host tissue and the ability to elaborate a polysaccharide capsule are critical determinants of diseas...

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Bibliographic Details
Main Authors: Won Hee Jung, Sanjay Saikia, Guanggan Hu, Joyce Wang, Carlen Ka-Yin Fung, Cletus D'Souza, Rick White, James W Kronstad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2991262?pdf=render