Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5.

Mitochondria are indispensable in the life and death of many types of eukaryotic cells. In pancreatic beta cells, mitochondria play an essential role in the secretion of insulin, a hormone that regulates blood glucose levels. Unregulated blood glucose is a hallmark symptom of diabetes. The onset of...

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Bibliographic Details
Main Authors: Yaíma L Lightfoot, Jing Chen, Clayton E Mathews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3124469?pdf=render