High CRLF2 Expression Could Identify Acute Lymphoblastic Leukemia Patients with Poor Outcome but Not IKZF1

Background: Overexpression of cytokine receptor-like factor 2 (CRLF2) caused by different genetic aberrations has been observed in acute lymphoblastic leukemia (ALL) and correlated with poor outcome. Most patients with high CRLF2 expression are clustered in the Philadelphia-like (Ph-like) ALL subgro...

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Bibliographic Details
Main Authors: Layla M. Saleh, Nour Darwish, Sherin Abdel-Aziz, Dalia Salem, Noha Eisa, Suzy Abd El Mabood, Maryan W. Fahmi, Ziad Emarah
Format: Article
Language:English
Published: Kasr Al-Ainy Center of Clinical Oncology and Nuclear Medicine 2021-06-01
Series:Research in Oncology
Subjects:
Online Access:https://resoncol.journals.ekb.eg/article_124161_46a1473683282955b21fd3160bdf9835.pdf