Regulatory Role of Small Nucleolar RNAs in Human Diseases

Small nucleolar RNAs (snoRNAs) are appreciable players in gene expression regulation in human cells. The canonical function of box C/D and box H/ACA snoRNAs is posttranscriptional modification of ribosomal RNAs (rRNAs), namely, 2′-O-methylation and pseudouridylation, respectively. A series of indepe...

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Bibliographic Details
Main Authors: Grigory A. Stepanov, Julia A. Filippova, Andrey B. Komissarov, Elena V. Kuligina, Vladimir A. Richter, Dmitry V. Semenov
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/206849