Dexmedetomidine protects against degeneration of dopaminergic neurons and improves motor activity in Parkinson's disease mice model

Parkinson’s disease (PD) is the result of dopaminergic (DA) neuronal death in the substantianigra pars compacta (SNc). Current treatments for PD such as L-dopa are limited in effectiveness and fail to address the cause. Targeted anti-inflammatory therapies, particularly directed at nuclear factor ka...

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Bibliographic Details
Main Authors: Bao-ping Zhang, Li Wu, Xian-wei Wu, Fang Wang, Xin Zhao
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Saudi Journal of Biological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X21002746