A New Algorithm for Identifying Cis-Regulatory Modules Based on Hidden Markov Model

The discovery of cis-regulatory modules (CRMs) is the key to understanding mechanisms of transcription regulation. Since CRMs have specific regulatory structures that are the basis for the regulation of gene expression, how to model the regulatory structure of CRMs has a considerable impact on the p...

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Bibliographic Details
Main Authors: Haitao Guo, Hongwei Huo
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/6274513