Serum miR371 in testicular germ cell cancer before and after orchiectomy, assessed by digital-droplet PCR in a prospective study

Abstract MicroRNA-371a-3p (miR371) has been suggested as a sensitive biomarker in testicular germ cell cancer (TGCC). We aimed to compare miR371 with the classical biomarkers α-fetoprotein (AFP) and β-human chorionic gonadotropin (hCGβ). Overall, 180 patients were prospectively enrolled in the study...

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Main Authors: Mette Pernille Myklebust, Anna Thor, Benedikte Rosenlund, Peder Gjengstø, Ása Karlsdottir, Marianne Brydøy, Bogdan S. Bercea, Christian Olsen, Ida Johnson, Mathilde I. Berg, Carl W. Langberg, Kristine E. Andreassen, Anders Kjellman, Hege S. Haugnes, Olav Dahl
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94812-2