'Multi-epitope-targeted' immune-specific therapy for a multiple sclerosis-like disease via engineered multi-epitope protein is superior to peptides.
Antigen-induced peripheral tolerance is potentially one of the most efficient and specific therapeutic approaches for autoimmune diseases. Although highly effective in animal models, antigen-based strategies have not yet been translated into practicable human therapy, and several clinical trials usi...
Main Authors: | Nathali Kaushansky, Nicole Kerlero de Rosbo, Rina Zilkha-Falb, Reut Yosef-Hemo, Lydia Cohen, Avraham Ben-Nun |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3226621?pdf=render |
Similar Items
-
DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-like disease: Potential role of DQB1*06:02 as a disease predisposing allele.
by: Nathali eKaushansky, et al.
Published: (2014-10-01) -
Multi-epitope peptide vaccines for human lymphatic filariasis
by: J. Madhumathi, et al.
Published: (2014-04-01) -
The Gut-Brain Axis in Multiple Sclerosis. Is Its Dysfunction a Pathological Trigger or a Consequence of the Disease?
by: Benedetta Parodi, et al.
Published: (2021-09-01) -
Development of a multi-epitope peptide vaccine against human leishmaniases
by: Da Silva Pissarra, Joana
Published: (2019) -
Immune-Informatic Analysis and Design of Peptide Vaccine From Multi-epitopes Against
by: Daniela Droppa-Almeida, et al.
Published: (2018-05-01)