'Multi-epitope-targeted' immune-specific therapy for a multiple sclerosis-like disease via engineered multi-epitope protein is superior to peptides.

Antigen-induced peripheral tolerance is potentially one of the most efficient and specific therapeutic approaches for autoimmune diseases. Although highly effective in animal models, antigen-based strategies have not yet been translated into practicable human therapy, and several clinical trials usi...

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Bibliographic Details
Main Authors: Nathali Kaushansky, Nicole Kerlero de Rosbo, Rina Zilkha-Falb, Reut Yosef-Hemo, Lydia Cohen, Avraham Ben-Nun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3226621?pdf=render