Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats

Epidermal Growth Factor Induces Vasoconstriction Through the Phosphatidylinositol 3-Kinase-Mediated Mitogen-Activated Protein Kinase Pathway in Hypertensive Rats

Abstract.: We investigated whether increased contractile responsiveness to epidermal growth factor (EGF) is associated with altered activation of mitogen-activated protein kinase (MAPK) in the aortic smooth muscle of deoxycorticosterone acetate (DOCA)-salt hypertensive rats. EGF induced contraction...

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Bibliographic Details
Main Authors: Kim Junghwan, Lee Chang-Kwon, Park Hyo-Jun, Kim Hyo Jin, So Hyun Ha, Lee Keun Sang, Lee Hwan Myung, Roh Hui Yul, Choi Wahn Soo, Park Tae Kyu, Kim Bokyung
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344585

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http://www.sciencedirect.com/science/article/pii/S1347861319344585

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