First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site

First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site

Abstract Background We measured whole body distribution of 11C-BU99008, a new PET biomarker for non-invasive identification of the imidazoline2 binding site. The purpose of this phase I study was to evaluate the biodistribution and radiation dosimetry of 11C-BU99008 in healthy human subjects. Method...

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Bibliographic Details
Main Authors: Ashwin V. Venkataraman, Nicholas Keat, James F. Myers, Samuel Turton, Inge Mick, Roger N. Gunn, Eugenii A. Rabiner, Jan Passchier, Christine A. Parker, Robin J. Tyacke, David J. Nutt
Format: Article
Language:English
Published: SpringerOpen 2018-07-01
Series:EJNMMI Research
Subjects:
Biodistribution
Dosimetry
Positron emission tomography
11C-BU99008
Imidazoline2
Online Access:http://link.springer.com/article/10.1186/s13550-018-0429-x

Internet

http://link.springer.com/article/10.1186/s13550-018-0429-x

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