Epitope-based vaccines with the Anaplasma marginale MSP1a functional motif induce a balanced humoral and cellular immune response in mice.

Bovine anaplasmosis is a hemoparasitic disease that causes considerable economic loss to the dairy and beef industries. Cattle immunized with the Anaplasma marginale MSP1 outer membrane protein complex presents a protective humoral immune response; however, its efficacy is variable. Immunodominant e...

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Bibliographic Details
Main Authors: Paula S Santos, Angela A S Sena, Rafael Nascimento, Thaise G Araújo, Mirian M Mendes, João R S Martins, Tiago W P Mineo, José R Mineo, Luiz R Goulart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620323?pdf=render