Interleukin-1beta and TNF-alpha: reliable targets for protective therapies in Parkinson´s Disease?

Neuroinflammation has received increased attention as a target for putative neuroprotective therapies in Parkinson´s Disease (PD). Two prototypic pro-inflammatory cytokines Interleukin-1beta (IL-1) and Tumor necrosis factor-alpha (TNF) have been implicated as main effectors of the functiona...

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Bibliographic Details
Main Authors: María Celeste Leal, Juan Cruz Casabona, Mariana ePuntel, FERNANDO ePITOSSI
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00053/full