Diatom-derived polyunsaturated aldehydes activate cell death in human cancer cell lines but not normal cells.

Diatoms are an important class of unicellular algae that produce bioactive polyunsaturated aldehydes (PUAs) that induce abortions or malformations in the offspring of invertebrates exposed to them during gestation. Here we compare the effects of the PUAs 2-trans,4-trans-decadienal (DD), 2-trans,4-tr...

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Bibliographic Details
Main Authors: Clementina Sansone, Alessandra Braca, Elena Ercolesi, Giovanna Romano, Anna Palumbo, Raffaella Casotti, Maria Francone, Adrianna Ianora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4081559?pdf=render