α 2-Adrenoceptors: Challenges and Opportunities—Enlightenment from the Kidney

It was indeed a Don Quixote-like pursuit of the mechanism of essential hypertension when we serendipitously discovered α2-adrenoceptors (α2-ARs) in skin-lightening experiments in the frog. Now α2-ARs lurk on the horizon involving hypertension causality, renal denervation for hypertension, injury fro...

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Bibliographic Details
Main Authors: William A. Pettinger, Edwin K. Jackson
Format: Article
Language:English
Published: Hindawi-Wiley 2020-01-01
Series:Cardiovascular Therapeutics
Online Access:http://dx.doi.org/10.1155/2020/2478781