Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx

Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx

Hepatitis B virus (HBV) remains a major cause of hepatic disease that threatens human health worldwide. Type I IFN (IFN-I) therapy is an important therapeutic option for HBV patients. The antiviral effect of IFN is mainly mediated via upregulation of the expressions of the downstream IFN-stimulated...

Full description

Bibliographic Details
Main Authors: Guangyun Tan, Fengchao Xu, Hongxiao Song, Ye Yuan, Qingfei Xiao, Feng Ma, F. Xiao-Feng Qin, Genhong Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
type I IFN
STAT1
TRIM14
hepatitis B virus X protein
hepatitis B virus replication
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01872/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01872/full

Similar Items