Anti-VEGF agents in metastatic colorectal cancer (mCRC): are they all alike?

Muhammad Wasif Saif GI Oncology Program, Tufts University School of Medicine, Boston, MA, USA Abstract: Bevacizumab is a monoclonal antibody that binds and neutralizes vascular endothelial growth factor (VEGF)-A, a key player in the angiogenesis pathway. Despite benefits of bevacizumab in cancer the...

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Bibliographic Details
Main Author: Saif MW
Format: Article
Language:English
Published: Dove Medical Press 2013-06-01
Series:Cancer Management and Research
Online Access:http://www.dovepress.com/anti-vegf-agents-in-metastatic-colorectal-cancer-mcrc-are-they-all-ali-a13312