Aberrant expression of HDL-bound microRNA induced by a high-fat diet in a pig model: implications in the pathogenesis of dyslipidaemia

Abstract Background A high-fat diet can affect lipid metabolism and trigger cardiovascular diseases. A growing body of studies has revealed the HDL-bound miRNA profiles in familial hypercholesterolaemia; in sharp contrast, relevant studies on high-fat diet-induced dyslipidaemia are lacking. In the c...

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Bibliographic Details
Main Authors: Guoyuan Sui, Lianqun Jia, Nan Song, Dongyu Min, Si Chen, Yao Wu, Guanlin Yang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Cardiovascular Disorders
Subjects:
HDL
Online Access:https://doi.org/10.1186/s12872-021-02084-5