Domain Organization of the UBX Domain Containing Protein 9 and Analysis of Its Interactions With the Homohexameric AAA + ATPase p97 (Valosin-Containing Protein)

Domain Organization of the UBX Domain Containing Protein 9 and Analysis of Its Interactions With the Homohexameric AAA + ATPase p97 (Valosin-Containing Protein)

The abundant homohexameric AAA + ATPase p97 (also known as valosin-containing protein, VCP) is highly conserved from Dictyostelium discoideum to human and a pivotal factor of cellular protein homeostasis as it catalyzes the unfolding of proteins. Owing to its fundamental function in protein quality...

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Bibliographic Details
Main Authors: Jana Riehl, Ramesh Rijal, Leonie Nitz, Christoph S. Clemen, Andreas Hofmann, Ludwig Eichinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
p97/VCP/CDC48/TER/VAT ATPase
UBX domain containing protein 9 (UBXD9
TUG
ASPL
PUX1)
IBMPFD (Inclusion Body Myopathy associated with Paget disease of bone and Fronto temporal Dementia)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.748860/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.748860/full

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