Precise regulation of gene expression dynamics favors complex promoter architectures.

Promoters process signals through recruitment of transcription factors and RNA polymerase, and dynamic changes in promoter activity constitute a major noise source in gene expression. However, it is barely understood how complex promoter architectures determine key features of promoter dynamics. Her...

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Bibliographic Details
Main Authors: Dirk Müller, Jörg Stelling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2615112?pdf=render