Infection decreases fatty acid oxidation and nuclear hormone receptors in the diaphragm

Respiratory failure is a major cause of mortality during septic shock and is due in part to decreased ventilatory muscle contraction. Ventilatory muscles have high energy demands; fatty acid (FA) oxidation is an important source of ATP. FA oxidation is regulated by nuclear hormone receptors; studies...

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Bibliographic Details
Main Authors: Kenneth R. Feingold, Arthur Moser, Sophie M. Patzek, Judy K. Shigenaga, Carl Grunfeld
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307136