RNA biology of disease-associated microsatellite repeat expansions

RNA biology of disease-associated microsatellite repeat expansions

Abstract Microsatellites, or simple tandem repeat sequences, occur naturally in the human genome and have important roles in genome evolution and function. However, the expansion of microsatellites is associated with over two dozen neurological diseases. A common denominator among the majority of th...

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Bibliographic Details
Main Authors: Kushal J. Rohilla, Keith T. Gagnon
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Acta Neuropathologica Communications
Subjects:
Repeat expansion disease
Microsatellite
Tandem repeats
RNA
Splicing
Transcription
Online Access:http://link.springer.com/article/10.1186/s40478-017-0468-y

Internet

http://link.springer.com/article/10.1186/s40478-017-0468-y

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