Pathogenesis and Targeted Therapy of Epilepsy

Pathogenesis and Targeted Therapy of Epilepsy

Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respon...

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Bibliographic Details
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
Medicine and Nursing
Neurosciences
3-phosphoinositide-dependent protein kinase-1
3CAI
4-aminopyridine
acoustically evoked seizures
AKT
AMPA receptor
anxiety
astrocyte
audiogenic epilepsy
audiogenic kindling
behavior genetics
blood-brain barrier
c-Fos
cortical atrophy
cyclosporin A
cytokine
EACT
early gene activation
epilepsy
epilepsy model
epileptogenesis
fear reaction
generalized tonic-clonic seizures
ghrelin
ghrelin receptor
GluA1
GluR1
GRIA1
GRIA2
hippocampal atrophy
hippocampus
immunofluorescence
inherited epilepsy
intracerebral electrode
intractable epilepsy
lipopolysaccharide
long-term potentiation
magnetic resonance imaging
ML365
mural cells
n/a
neuroinflammation
neuronal activity
neuropsychiatric comorbidity
PDK1
pentylenetetrazole
pericytes
pharmacoresistant epilepsy
PICK1
post-traumatic epilepsy
posttraumatic epilepsy
protein kinase C
refractory seizure
rodents
seizure susceptibility
temporal lobe epilepsy
TMEM1A channels
traumatic brain injury
TRPV1 channels
wild running seizures
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